In her 1962 groundbreaking book Silent Spring, Rachel
Carson wrote: “For the first time in the history of the
world every human being is now subjected to contact with
dangerous chemicals, from the moment of conception
until death.” Of course humans have always been
exposed to potentially harmful chemicals from plants and
other sources, but Rachel Carson’s point is well taken.
Modern living exposes all of us to an unprecedented number
of chemicals on a daily basis. This includes environmental
toxins such as heavy metals, pesticides, industrial compounds
and chemical byproducts, medications, cosmetic additives,
inorganic chemicals, etc. These chemical substances, which are
foreign to the biological system, are referred to as “xenobiotics.”
The good news is that the body was designed to detoxify
and excrete xenobiotics. The bad news is our bodies may
not always be equipped to handle the volume of modern
environmental pollutants and toxic substances. This problem
may be exacerbated by the fact that the refining of many of our
foodstuffs has caused them to provide considerably less of the
nutrients that are essential to the detoxification process.1,2
Ramifications of toxic overload
The ramifications of toxic overload can vary from one individual
to another. One possible ramification is multiple chemical
sensitivities (MCS). MCS is a condition in which a person
experiences various symptoms in response to being exposed to certain types of chemicals, primarily (but not limited to) those of
petroleum and coal-tar derivation. The possible symptoms are
many and may include headaches, fatigue, depression and an
overall feeling of malaise and being sick. MCS seems to develop
after consistent, long-term exposure to certain chemicals at
home or in the workplace. Eventually, the person develops
intolerance to these chemicals, and starts suffering from MCS.
For many MCS people, a sensitivity reaction will occur when
exposed to even minute amounts of the offending chemicals,
which in turn, can lead to severe symptoms characteristic of the
MCS condition.3
Of course, an individual may suffer from toxic overload
without having full-blown MCS. In fact, the most common
symptom of toxic overload is probably fatigue. Other common
symptoms include headache, muscle and joint pain, irritability,
depression, mental confusion, gastrointestinal and/or
cardiovascular irregularities, flu-like symptoms or allergic
reactions including hives, stuffy or runny nose, sneezing and
coughing.4,5
Furthermore, some researchers have suggested that toxic
overload may contribute to autoimmune diseases including
inflammatory and rheumatoid arthritis,6,7 and neurological
diseases such as Alzheimer’s and Parkinson’s.8
How to deal with toxic overload
The question of how to deal with toxic overload has a multi-part
answer, which includes adapting to a healthier diet and reducing
exposure to xenobiotics. The books Multiple Chemical Sensitivity
by Gibson (2000, New Harbinger Publications, Inc.) and Staying
Well in a Toxic World by Lawson (1993, The Nobel Press) provide
good direction on how to do this. In addition there are four
herbal teas, which if used correctly, may do much to help support
and promote the body’s natural detoxification process. These
teas include ginger root (rhizome), green tea, dandelion root
and senna. Following is a discussion about the role that each of
these herbal teas can play, including a subsequent explanation
of how to use them as part of a detox program.
Circulation and ginger
Healthy circulation is of vital importance to an effective
detoxification process.9 The fundamental reason for this is that
toxins and metabolic wastes are flushed out of tissues and into
circulation so they can be detoxified.10 If circulation is sluggish
and toxins move more slowly through it, however, this may
result in undesirable symptoms such as headache and fatigue.11
The root or rhizome (enlarged underground stem) of ginger
(Zingiber officinale) is an herbal medicine that is valuable for
the treatment of multiple problems, especially nausea. In fact,
ginger has been reported to be effective in treating the nausea
of seasickness, morning sickness and chemotherapy-induced
nausea.12 Ginger is also a traditional carminative (gas relieving)
herb,13 and has anti-inflammatory properties.14
For the purposes of detoxification, ginger is valuable since it
promotes circulation, and has long been used for this purpose
in Traditional Chinese Medicine. In fact, the most famous
traditional medicinal practice of ginger is to promote the blood
circulation for removing blood stasis and the mechanism is
related to anti-platelet aggregation activity. In addition, ginger
has a stimulatory action on heart muscle promoting circulation
throughout the body. That increased circulation is thought to
stimulate cellular metabolic activity.15,16
Liver detoxification pathways and green tea
Water-soluble toxins can pass through our bodies unchanged
and be eliminated in the stool, sweat or urine. Fat-soluble
toxins, however, cannot be excreted without undergoing
metabolic transformation (detoxification) in the liver so that
they can become water-soluble. Liver cells have sophisticated
mechanisms to break down toxic substances. These include
both endogenous (produced by the body) and exogenous
(obtained from the environment; i.e., xenobiotics) substances.
Every drug, chemical, pesticide and hormone, is broken down or
metabolized via detoxification pathways in the liver called “phase
1” and “phase 2.” 17,18,19 During phase 1, a “functional group”
is removed from the toxic molecule,20,21 and during phase 2 a
water-soluble substance is coupled (attaching) or conjugated to
the toxin. This makes the toxic molecule more water-soluble and
therefore less toxic. If the molecule is large, it is then excreted via
the bile. Otherwise, it is excreted in the urine.22,23
Green, Oolong and black tea are all made from the leaves of
the same plant species, Camellia sinensis. Green tea, the world’s
second most popular beverage after water, is perhaps best
known for its antioxidant and thermogenic properties. It is the
polyphenols in green tea, specifically the catechin polyphenols,
which gives it biological and medicinal qualities.24
In fact, green tea polyphenols increase both phase 1 and
phase 2 activities.25 Research shows that green tea may have liver
protective properties.26,27,28,29 In addition, Green tea has been
shown to block chromosomal (DNA) damage from chemicals
in cigarette smoke.30 Perhaps not surprisingly, green tea
polyphenols are associated with a reduced risk of certain cancers
in humans.31 Other research has also shown an anticancer effect
from these polyphenols,32 including an inhibition of metastasis
in skin cancer cells.33 In short, the use of green tea helps improve
phase 1 and 2 liver detoxification pathways.
Bile flow and dandelion root
Bile is a digestive aid for fats, produced by the liver and
transported to the gallbladder where it is concentrated. It then
passes through the common bile duct into the intestines where
it helps digest fat.34 From the standpoint of detoxification, bile
also has a function as previously stated: it serves as a vehicle
for disposing of toxic molecules that are too large for disposal
via urine.35,36 Essentially, those toxins just hitch a ride until they
reach the intestines where they can ultimately be excreted.
Dandelion root (Taraxacum officinale) is a traditionally used
liver herb that has been shown to help stimulate bile production
and promote its flow.37,38 This supports the aforementioned
detoxification process via the bile duct, promoting the
elimination of wastes.39 In fact, Germany and other official
European health agencies have approved the use of Dandelion
root for disturbances in bile flow, and restoration of hepatic and
biliary function.40
Intestinal waste elimination and senna
It is well understood that waste is excreted from the intestines or, more specifically, the colon. During this process, bile that was
secreted into the intestines is also excreted. Since that bile also
contains some toxins that hitched a ride, it makes sense to make
sure that it does not linger for too long in the gut, otherwise
some of the toxins may be re-absorbed (clearly not a good thing).
Constipation is the most obvious cause of waste lingering too
long in the gut.
Senna leaf (Senna alexandrina) is used extensively as a natural
laxative, and has been shown in research to be effective for this
purpose and for reducing constipation.41,42,43,44 Furthermore,
when used appropriately on a short-term basis, senna has
been shown to have a good safety profile.45,46 Sennosides, the
active compounds in senna, are not absorbed, but instead
are activated by bacterial enzymes in the colon.47 The result is
that senna exerts its laxative effect by inducing fluid secretion,
which increases colonic motility and colonic transit.48 In some
instances, senna can cause abdominal pain and discomfort,
cramps, and diarrhea;49,50 so it is important not to exceed
recommended doses.
Directions on how to use the teas
Following are directions on how to use the herbal teas discussed
in this article. First, make sure to use only organic teas since
there is no point in adding additional toxins to the body in the
form of pesticides that may have otherwise been sprayed on
non-organic herbs. Second, assume that all of the teas should be
made by adding one tea bag in a cup and adding eight ounces of
boiling water. The steep time and number of servings will differ
depending upon the herb (as indicated below):

As long as you steep the teas according to the times
indicated, it is acceptable to consume them hot or cold (as
iced tea). If you like, you can even mix the brewed ginger root,
Green tea and dandelion root (but not the senna) into a single
beverage to make it easier to drink. In either case, it will probably
be more convenient for you to brew all of the tea for the day
in the morning, rather than having to brew it at three different
times during the day (unless you’d like to do it that way). In the
case of senna, it would be best to brew and consume the single
serving in the evening before bedtime.
These herbal teas can be used to support detoxification for
as little as two weeks or for up to one month. A twice annual
“Spring and Fall cleaning” is recommended.
Other considerations
The herbal teas discussed in this article are certainly not the
only natural products capable of supporting and facilitating
the detoxification process. Compounds from citrus fruit and
the Brassica or cruciferous group of vegetables (e.g., cabbage,
Brussels sprouts, broccoli, etc.), as well as the dietary supplement
alpha lipoic acid are some examples of other effective detoxifying
agents.51 Nevertheless, the teas discussed in this article can be
effective adjuncts to a program for detoxification.
In addition, it would make good sense to eat a diet high
in fruit and vegetables, drink plenty of liquids and get at least
25 grams of fiber per day to support overall detoxification.
Finally, it should be noted that the use of these teas as part of a
detoxification program are meant to be used for general health
and wellness purposes. If you have a serious health condition,
you should seek the help of a healthcare professional who is
knowledgeable about the process before starting a detoxification
program.
References:
- Rogers SA. Chemical Sensitivity: Breaking the Paralyzing Paradigm. Internal Medicine World Report1992; February 1-14:15-16.
- Rogers SA. Chemical Sensitivity: Breaking the Paralyzing Paradigm. Internal Medicine World Report1992; March 15-31: 8-31.
- Lawson L. Staying Well in a Toxic World. Chicago: The Nobel Press, Inc.; 1993.
- Lawson L. Staying Well in a Toxic World. Chicago: The Nobel Press, Inc.; 1993.
- Gibson PR. Multiple Chemical Sensitivity. Oakland, California: New Harbinger Publications, Inc.; 2000.
- Rooney PJ, Jenkins RT, Buchanan WW. A short review of the relationship between intestinal permeability and inflammatory joint disease. Clinical and Experimental Rheumatology 1990; 8(1):75–83.
- Smith MD, Gibson RA, Brooks PM. Abnormal bowel permeability in ankylosing spondylitis and rheumatoid arthritis. Journal of Rheumatology 1985; 12(2):299–305.
- Steventon, GB, Heafield MT, Sturman S, Waring RH, Williams AC. Xenobiotic metabolism in Alzheimer’s disease. Neurology, 1990;40(7):1095–8.
- Hyman M. Systems Biology, Toxins, Obesity, and Functional Medicine. Proceedings from the 13th International Symposium of The Institute for Functional Medicine. 2006:S134–9.
- Posadzki P, Smith TO, Lizis P. Lomi Lomi as a massage with movements: A conceptual synthesis? Altern Ther. 2009;15(6):44–9.
- Roundtree R. A functional approach to environmental toxins. Alternat Complement Ther. 2009;15(5):216–20.
- Ernst E, Pittler MH. Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials. British Journal of Anaesthesia 2000; 84(3):367–71.
- Blumenthal M, et al, (eds), The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications;1998:425–26.
- Srivastava KC, Mustafa T. Med Hypotheses. 1992;39(4):342–8.
- Ghosh AK. Zingiber officinale: a natural gold. IJPBS. 2011;2(1):283–94.
- Zadeh JB, Kor NM. Physiological and pharmaceutical effects of Ginger (Zingiber officinale Roscoe) as a valuable medicinal plant. Eur J Exp Biol. 2014;4(1):87–90.
- Murray Rk, Granner DK, Mayes PA, Rodwell VW. Harper’s Biochemistry, 25th ed. New York: McGraw Hill; 1999:780–6.
- Lüllmann H. Mohr K, Ziegler A, Bieger D. Color Atlas of Pharmacology, 2nd ed. Stuttgart: Thieme; 2000:32–9.
- Roundtree R. The Use of Phytochemicals in the Biotransformation and Elimination of Environmental Toxins. IN Medicines from the Earth 2003: Official Proceedings. Brevard, North Carolina: Gaia Herbal Research Institute;2003:115–128.
- Murray Rk, Granner DK, Mayes PA, Rodwell VW. Harper’s Biochemistry, 25th ed. New York: McGraw Hill; 200:780–6.
- Lüllmann H. Mohr K, Ziegler A, Bieger D. Color Atlas of Pharmacology, 2nd ed. Stuttgart: Thieme; 2000:32–9.
- Murray Rk, Granner DK, Mayes PA, Rodwell VW. Harper’s Biochemistry, 25th ed. New York: McGraw Hill; 200:780–6.
- Lüllmann H. Mohr K, Ziegler A, Bieger D. Color Atlas of Pharmacology, 2nd ed. Stuttgart: Thieme; 2000:32–9.
- Graham HN. Green tea composition, consumption, and polyphenol chemistry. Prev Med 1992;21:334–50.
- Stoner GD, Mukhtar H. Polyphenols as cancer chemopreventive agents. J Cell Biochem Suppl 1995; 22:169–80.
- Presser A. Pharmacist’s Guide to Medicinal Herbs. Petaluma, California: Smart Publications; 2000.
- Kuhn MA, Winston D. Herbal Therapy & Supplements: A Scientific & Traditional Approach. Philadelphia:Lippincott; 2000.
- Mills S, Bone K. Principles and Practice of Phytotherapy: Edinburgh;Churchill Livingstone; 2000.
- Blumenthal M, Goldberg A, Brinckmann J (eds). Herbal Medicine: Expanded Commission E Monographs: Newton, Massachusetts;Integrative Medicine Communications; 2000.
- Shim JS, Kang MH, Kim YH, Roh JK, Roberts C, Lee IP. Chemopreventive effect of green tea (Camellia sinensis) amonth cigarette smokers. Cancer Epidemiol Biomakers Prev 1995; 4(4):387–91.
- Mukhtar H, Ahmad N. Green tea in chemoprevention of cancer. Toxicol Sci 1999;52(2 Suppl):111–7.
- Suganuma M, Okabe S, Sueoka N, et al. Green tea and cancer chemoprevention. Mutat Res 1999;428:339–44.
- Menon LG, Kuttan R, Kuttan G. Anti-metastatic activity of curcumin and catechin. Cancer Lett1999;141:159–65.
- Afdhal NH. Diseases of the gallbladder and bile ducts. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011.
- Murray Rk, Granner DK, Mayes PA, Rodwell VW. Harper’s Biochemistry, 25th ed. New York: McGraw Hill; 2000:780-786.
- Lüllmann H. Mohr K, Ziegler A, Bieger D. Color Atlas of Pharmacology, 2nd ed. Stuttgart: Thieme; 2000:32–9.
- Vogel G. Natural substances with effects on the liver. In: Wagner H, Wolff P (eds). New Natural Products and Plant Drugs with Pharmacological, Biological or Therapeutic Activity. Heidelberg: Springer-Verlag; 1977.
- Tierra M. International Journal of Alternative and Complementary Medicine. 1997; February:23–5.
- Salmond S. Australian Journal of Medical Herbalism. 1997;9(1):14–8.
- Blumenthal M, Goldberg A, Brinckman J (eds). Herbal Medicine: Expanded Commission E Monographs. Newton, Massachusetts: Integrative Medicine Communications; 2000:78–83.
- Godding EW. Laxatives and the special role of senna. Pharmacology 1988;36:230–6.
- Ramesh PR, Kumar KS, Rajagopal MR, et al. Managing morphine-induced constipation: a controlled comparison of an Ayurvedic formulation and senna. J Pain Symptom Manage 1998;16:240–4.
- Shelton MG. Standardized senna in the management of constipation in the puerperium: A clinical trial. S Afr Med J 1980;57:78-80.
- MacLennan WJ, Pooler AFWM. A comparison of sodium picosulphate (“Laxoberal”) with standardised senna (“Senokot”) in geriatric patients. Curr Med Res Opin. 1974;2:641–7.
- Godding EW. Laxatives and the special role of senna. Pharmacology 1988;36:230–6.
- Arezzo A. Prospective randomized trial comparing bowel cleaning preparations for colonoscopy. Surg Laparosc Endosc Percutan Tech. 2000;10:215–7.
- Godding EW. Laxatives and the special role of senna. Pharmacology 1988;36:230–6.
- Ewe K, Ueberschaer B, Press AG. Influence of senna, fibre, and fibre + senna on colonic transit in loperamide-induced constipation. Pharmacology1993;47:242–8.
- Langmead L, Rampton DS. Review article: herbal treatment in gastrointestinal and liver disease--benefits and dangers. Aliment Pharmacol Ther 2001;15:1239–52.
- Sondheimer JM, Gervaise EP. Lubricant versus laxative in the treatment of chronic functional constipation of children: a comparative study. J Pediatr Gastroenterol Nutr 1982;1:223–6.
- Roundtree R. The Use of Phytochemicals in the Biotransformation and Elimination of Environmental Toxins. IN Medicines from the Earth 2003: Official Proceedings. Brevard, North Carolina: Gaia Herbal Research Institute; 2003:115–28.